MolNFT v1 · #457890 · protein
AlphaFold monomer V2.0 prediction for antigen peptide transporter 1 (P36370)
P36370: “AlphaFold monomer V2.0 prediction for antigen peptide transporter 1 (P36370)”. 7 pockets (best druggability 0.77). MolNFT v1 #457890 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P36370
- Type
- protein
- Length
- 725 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Antigen peptide transporter 1
- UniProt
- P36370
- Pockets
- 7 · best druggability 0.77
Structure
1 distinct chain · 68% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Antigen peptide transporter 1 | protein | 725 | 68% helix, 9% strand | P36370 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1092 | 0.77 | 0.79 | 107 | empty |
| 2 | 619 | 0.65 | 0.76 | 61 | empty |
| 3 | 79 | 0.42 | 0.80 | 14 | empty |
| 4 | 53 | 0.38 | 0.80 | 14 | empty |
| 5 | 70 | 0.36 | 0.77 | 16 | empty |
Compared structures
- 4K8O · Crystal structure of the ATPase domain of TAP1 with ATP (D645N, D651A mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 4K8O · Crystal structure of the ATPase domain of TAP1 with ATP (D645N, D651A mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 2IXF · Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant) · an experimental structure of the same protein · chain A against C, TM-score 0.34
- 2IXF · Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant) · an experimental structure of the same protein · chain A against C, TM-score 0.34
- 2IXE · Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.34
- 2IXE · Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.34
- 2IXG · Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.34
- 2IXG · Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant) · an experimental structure of the same protein · chain A against A, TM-score 0.34
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36370
- Elsewhere: UniProt P36370 · AlphaFold DB P36370
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