MolNFT v1 · #457875 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase TAO2 (Q9JLS3)
Q9JLS3: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase TAO2 (Q9JLS3)”. 9 pockets (best druggability 0.78). MolNFT v1 #457875 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9JLS3
- Type
- protein
- Length
- 1,235 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- SERINE/THREONINE-protein kinase TAO2
- UniProt
- Q9JLS3
- Pockets
- 9 · best druggability 0.78
Structure
1 distinct chain · 46% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase TAO2 | protein | 1235 | 46% helix, 5% strand | Q9JLS3 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1057 | 0.78 | 0.80 | 87 | empty |
| 2 | 273 | 0.50 | 0.73 | 22 | empty |
| 3 | 120 | 0.38 | 0.73 | 17 | empty |
| 4 | 76 | 0.33 | 0.75 | 16 | empty |
| 5 | 71 | 0.31 | 0.74 | 13 | empty |
Compared structures
- 1U5R · Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 1U5R · Crystal structure of the TAO2 kinase domain: activation and specifity of a STE20P MAP3K · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 2GCD · TAO2 kinase domain-staurosporine structure · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 2GCD · TAO2 kinase domain-staurosporine structure · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 1U5Q · Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 1U5Q · Crystal structure of the TAO2 kinase domain: activation and specifity of a STE20P MAP3K · an experimental structure of the same protein · chain A against A, TM-score 0.25
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JLS3
- Elsewhere: UniProt Q9JLS3 · AlphaFold DB Q9JLS3
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