MolNFT v1 · #454050 · protein

AlphaFold monomer V2.0 prediction for synaptotagmin-4 (P50232)

P50232: “AlphaFold monomer V2.0 prediction for synaptotagmin-4 (P50232)”. 3 pockets (best druggability 0.47). MolNFT v1 #454050 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P50232
Type: protein
Length: 425 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
Molecule: Synaptotagmin-4
UniProt: P50232
Pockets: 3 · best druggability 0.47

Structure

1 distinct chain · 10% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Synaptotagmin-4	protein	425	10% helix, 32% strand	P50232

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	233	0.47	0.73	37	empty
2	91	0.36	0.75	14	empty
3	57	0.30	0.75	13	empty

Compared structures

1W15 · rat synaptotagmin 4 C2B domain in the presence of calcium · an experimental structure of the same protein · chain A against A, TM-score 0.31
1W15 · Rat synaptotagmin 4 C2B domain in the presence of calcium · an experimental structure of the same protein · chain A against A, TM-score 0.31
1W16 · rat synaptotagmin 4 C2B domain in the absence of calcium · an experimental structure of the same protein · chain A against A, TM-score 0.29
1W16 · Rat synaptotagmin 4 C2B domain in the absence of calcium · an experimental structure of the same protein · chain A against A, TM-score 0.29

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50232
Elsewhere: UniProt P50232 · AlphaFold DB P50232

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