GL1X · GenesisL1 explorer

MolNFT v1 · #453751 · protein

AlphaFold monomer V2.0 prediction for serine--tRNA ligase (O58441)

O58441: “AlphaFold monomer V2.0 prediction for serine--tRNA ligase (O58441)”. 3 pockets (best druggability 0.73). MolNFT v1 #453751 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O58441
Type
protein
Length
455 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
Serine--tRNA ligase
UniProt
O58441
Pockets
3 · best druggability 0.73

Structure

1 distinct chain · 47% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASerine--tRNA ligaseprotein45547% helix, 21% strandO58441

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16750.730.8056empty
21030.370.7417empty
3630.320.7514empty

Compared structures

  • 2ZR3 · Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2ZR3 · Crystal structure of seryl-tRNA synthetase from pyrococcus horikoshii · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2DQ0 · Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with a… · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2DQ0 · Crystal structure of seryl-tRNA synthetase from pyrococcus horikoshii complexed with a… · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2ZR2 · Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with ATP · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2ZR2 · Crystal structure of seryl-tRNA synthetase from pyrococcus horikoshii complexed with ATP · an experimental structure of the same protein · chain A against A, TM-score 0.96

Analyse

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