MolNFT v1 · #451810 · protein
AlphaFold monomer V2.0 prediction for proline--tRNA ligase (Q74IS2)
Q74IS2: “AlphaFold monomer V2.0 prediction for proline--tRNA ligase (Q74IS2)”. 4 pockets (best druggability 0.70). MolNFT v1 #451810 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q74IS2
- Type
- protein
- Length
- 565 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x42b99fCBf328028516680849Fb75A6A83F1A1bF1
- Molecule
- Proline--tRNA ligase
- UniProt
- Q74IS2
- Pockets
- 4 · best druggability 0.70
Structure
1 distinct chain · 30% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proline--tRNA ligase | protein | 565 | 30% helix, 30% strand | Q74IS2 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 587 | 0.70 | 0.79 | 57 | empty |
| 2 | 153 | 0.58 | 0.82 | 21 | empty |
| 3 | 60 | 0.36 | 0.79 | 16 | empty |
| 4 | 53 | 0.26 | 0.73 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74IS2
- Elsewhere: UniProt Q74IS2 · AlphaFold DB Q74IS2
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