MolNFT v1 · #451118 · protein

AlphaFold monomer V2.0 prediction for synaptojanin-2 (O15056)

O15056: “AlphaFold monomer V2.0 prediction for synaptojanin-2 (O15056)”. 17 pockets (best druggability 0.86). MolNFT v1 #451118 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O15056
Type: protein
Length: 1,496 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x80fFD76c298b93E8762b4d46AD7aBea1fcDf9723
Molecule: Synaptojanin-2
UniProt: O15056
Pockets: 17 · best druggability 0.86

Structure

1 distinct chain · 24% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Synaptojanin-2	protein	1496	24% helix, 19% strand	O15056

Pockets

17 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1054	0.86	0.87	89	empty
2	500	0.73	0.82	46	empty
3	267	0.70	0.85	36	empty
4	241	0.69	0.85	36	empty
5	339	0.64	0.80	38	empty

Compared structures

1UFW · Solution structure of rnp domain in synaptojanin 2 · an experimental structure of the same protein · chain A against A, TM-score 0.06
1UFW · Solution structure of RNP domain in Synaptojanin 2 · an experimental structure of the same protein · chain A against A, TM-score 0.06

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O15056
Elsewhere: UniProt O15056 · AlphaFold DB O15056

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