MolNFT v1 · #451025 · protein
AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (P23395)
P23395: “AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (P23395)”. 4 pockets (best druggability 0.74). MolNFT v1 #451025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P23395
- Type
- protein
- Length
- 618 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
- Molecule
- Methionine--tRNA ligase
- UniProt
- P23395
- Pockets
- 4 · best druggability 0.74
Structure
1 distinct chain · 43% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine--tRNA ligase | protein | 618 | 43% helix, 21% strand | P23395 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 793 | 0.74 | 0.78 | 61 | empty |
| 2 | 156 | 0.56 | 0.81 | 19 | empty |
| 3 | 51 | 0.40 | 0.82 | 14 | empty |
| 4 | 52 | 0.28 | 0.74 | 13 | empty |
Compared structures
- 2D5B · Crystal Structure of Thermus Thermophilus Methionyl tRNA synthetase Y225F Mutant obtained… · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 2D5B · Crystal structure of thermus thermophilus methionyl tRNA synthetase Y225F mutant obtained… · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1A8H · Methionyl-tRNA synthetase from thermus thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1A8H · Methionyl-tRNA synthetase from thermus thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 2D54 · Crystal structure of methionyl tRNA synthetase Y225A mutant from thermus thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 2D54 · Crystal Structure of Methionyl tRNA Synthetase Y225A Mutant from Thermus Thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 3VU8 · Metionyl-tRNA synthetase from Thermus thermophilus complexed with methionyl-adenylate… · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 3VU8 · Metionyl-tRNA synthetase from thermus thermophilus complexed with methionyl-adenylate… · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 1WOY · Crystal structure of methionyl tRNA synthetase Y225F mutant from thermus thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 1WOY · Crystal structure of methionyl tRNA synthetase Y225F mutant from Thermus thermophilus · an experimental structure of the same protein · chain A against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23395
- Elsewhere: UniProt P23395 · AlphaFold DB P23395
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