MolNFT v1 · #450901 · protein

AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q9HYC7)

Q9HYC7: “AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q9HYC7)”. 3 pockets (best druggability 0.62). MolNFT v1 #450901 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9HYC7
Type: protein
Length: 677 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xDD3e63910080aF99E09988eCd7428CfA2293d53d
Molecule: Methionine--tRNA ligase
UniProt: Q9HYC7
Pockets: 3 · best druggability 0.62

Structure

1 distinct chain · 42% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methionine--tRNA ligase	protein	677	42% helix, 21% strand	Q9HYC7

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	287	0.62	0.80	36	empty
2	189	0.52	0.77	30	empty
3	57	0.32	0.76	11	empty

Compared structures

7ULZ · Crystal structure of methionine-tRNA ligase / methionyl-tRNA synthetase (metrs) from… · an experimental structure of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HYC7
Elsewhere: UniProt Q9HYC7 · AlphaFold DB Q9HYC7

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