MolNFT v1 · #450864 · protein
AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q74MZ1)
Q74MZ1: “AlphaFold monomer V2.0 prediction for methionine--tRNA ligase (Q74MZ1)”. 6 pockets (best druggability 0.72). MolNFT v1 #450864 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q74MZ1
- Type
- protein
- Length
- 776 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xCD02372865c553eFF897aF289Ecf524a0ff9D69e
- Molecule
- Methionine--tRNA ligase
- UniProt
- Q74MZ1
- Pockets
- 6 · best druggability 0.72
Structure
1 distinct chain · 41% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine--tRNA ligase | protein | 776 | 41% helix, 21% strand | Q74MZ1 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 684 | 0.72 | 0.78 | 71 | empty |
| 2 | 87 | 0.40 | 0.78 | 17 | empty |
| 3 | 84 | 0.38 | 0.77 | 15 | empty |
| 4 | 97 | 0.37 | 0.75 | 23 | empty |
| 5 | 72 | 0.29 | 0.72 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5H34 · Crystal structure of the C-terminal domain of methionyl-tRNA synthetase (metrs-C) in… · an experimental structure of the same protein · chain A against A, TM-score 0.14
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74MZ1
- Elsewhere: UniProt Q74MZ1 · AlphaFold DB Q74MZ1
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