MolNFT v1 · #450585 · protein
AlphaFold monomer V2.0 prediction for methionine--tRNA ligase, mitochondrial (O74634)
O74634: “AlphaFold monomer V2.0 prediction for methionine--tRNA ligase, mitochondrial (O74634)”. 4 pockets (best druggability 0.78). MolNFT v1 #450585 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O74634
- Type
- protein
- Length
- 577 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- Methionine--tRNA ligase, mitochondrial
- UniProt
- O74634
- Pockets
- 4 · best druggability 0.78
Structure
1 distinct chain · 49% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine--tRNA ligase, mitochondrial | protein | 577 | 49% helix, 17% strand | O74634 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 752 | 0.78 | 0.82 | 70 | empty |
| 2 | 55 | 0.31 | 0.76 | 15 | empty |
| 3 | 59 | 0.30 | 0.75 | 13 | empty |
| 4 | 60 | 0.29 | 0.75 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74634
- Elsewhere: UniProt O74634 · AlphaFold DB O74634
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