MolNFT v1 · #450365 · protein
AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (A8H7C2)
A8H7C2: “AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (A8H7C2)”. 8 pockets (best druggability 0.80). MolNFT v1 #450365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8H7C2
- Type
- protein
- Length
- 859 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x65b42577b5Bb934B59afF2aA701E1BA18026B799
- Molecule
- Leucine--tRNA ligase
- UniProt
- A8H7C2
- Pockets
- 8 · best druggability 0.80
Structure
1 distinct chain · 39% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine--tRNA ligase | protein | 859 | 39% helix, 23% strand | A8H7C2 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 796 | 0.80 | 0.83 | 80 | empty |
| 2 | 505 | 0.77 | 0.84 | 52 | empty |
| 3 | 89 | 0.53 | 0.84 | 17 | empty |
| 4 | 80 | 0.46 | 0.81 | 19 | empty |
| 5 | 90 | 0.38 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8H7C2
- Elsewhere: UniProt A8H7C2 · AlphaFold DB A8H7C2
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