MolNFT v1 · #450223 · protein
AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (A6LGA2)
A6LGA2: “AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (A6LGA2)”. 11 pockets (best druggability 0.78). MolNFT v1 #450223 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A6LGA2
- Type
- protein
- Length
- 946 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xddD89F6cedc3679f21663f3046B4aB3D5161E34E
- Molecule
- Leucine--tRNA ligase
- UniProt
- A6LGA2
- Pockets
- 11 · best druggability 0.78
Structure
1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine--tRNA ligase | protein | 946 | 39% helix, 21% strand | A6LGA2 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 814 | 0.78 | 0.81 | 70 | empty |
| 2 | 198 | 0.63 | 0.83 | 25 | empty |
| 3 | 139 | 0.57 | 0.83 | 23 | empty |
| 4 | 163 | 0.52 | 0.79 | 24 | empty |
| 5 | 77 | 0.51 | 0.84 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6LGA2
- Elsewhere: UniProt A6LGA2 · AlphaFold DB A6LGA2
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