MolNFT v1 · #449080 · protein

AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (A4XQV5)

A4XQV5: “AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (A4XQV5)”. 7 pockets (best druggability 0.72). MolNFT v1 #449080 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4XQV5
Type: protein
Length: 943 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7Be4C5B3cE1a26874f0703a2AeAd5Eb8910912Fc
Molecule: Isoleucine--tRNA ligase
UniProt: A4XQV5
Pockets: 7 · best druggability 0.72

Structure

1 distinct chain · 45% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoleucine--tRNA ligase	protein	943	45% helix, 18% strand	A4XQV5

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	590	0.72	0.80	56	empty
2	549	0.71	0.80	44	empty
3	81	0.54	0.86	26	empty
4	113	0.47	0.79	16	empty
5	123	0.46	0.78	19	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4XQV5
Elsewhere: UniProt A4XQV5 · AlphaFold DB A4XQV5

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