MolNFT v1 · #448882 · protein
AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (A7ZVX4)
A7ZVX4: “AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (A7ZVX4)”. 6 pockets (best druggability 0.75). MolNFT v1 #448882 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7ZVX4
- Type
- protein
- Length
- 938 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x41805e074c49e7dA35BdE142489deD42659C230F
- Molecule
- Isoleucine--tRNA ligase
- UniProt
- A7ZVX4
- Pockets
- 6 · best druggability 0.75
Structure
1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isoleucine--tRNA ligase | protein | 938 | 45% helix, 19% strand | A7ZVX4 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 868 | 0.75 | 0.79 | 74 | empty |
| 2 | 350 | 0.63 | 0.79 | 31 | empty |
| 3 | 152 | 0.49 | 0.78 | 21 | empty |
| 4 | 84 | 0.45 | 0.80 | 14 | empty |
| 5 | 86 | 0.34 | 0.74 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7ZVX4
- Elsewhere: UniProt A7ZVX4 · AlphaFold DB A7ZVX4
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