MolNFT v1 · #448051 · protein

AlphaFold monomer V2.0 prediction for histidine--tRNA ligase (Q2NIN2)

Q2NIN2: “AlphaFold monomer V2.0 prediction for histidine--tRNA ligase (Q2NIN2)”. 6 pockets (best druggability 0.74). MolNFT v1 #448051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q2NIN2
Type: protein
Length: 427 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
Molecule: Histidine--tRNA ligase
UniProt: Q2NIN2
Pockets: 6 · best druggability 0.74

Structure

1 distinct chain · 43% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histidine--tRNA ligase	protein	427	43% helix, 22% strand	Q2NIN2

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	565	0.74	0.81	55	empty
2	159	0.45	0.76	25	empty
3	123	0.43	0.76	25	empty
4	81	0.38	0.77	15	empty
5	52	0.36	0.80	12	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2NIN2
Elsewhere: UniProt Q2NIN2 · AlphaFold DB Q2NIN2

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