MolNFT v1 · #442443 · protein
AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2C (Q9Z2I6)
Q9Z2I6: “AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2C (Q9Z2I6)”. 3 pockets (best druggability 0.78). MolNFT v1 #442443 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Z2I6
- Type
- protein
- Length
- 727 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- Synaptic vesicle glycoprotein 2C
- UniProt
- Q9Z2I6
- Pockets
- 3 · best druggability 0.78
Structure
1 distinct chain · 63% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Synaptic vesicle glycoprotein 2C | protein | 727 | 63% helix, 8% strand | Q9Z2I6 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 114 | 0.78 | 0.97 | 22 | empty |
| 2 | 944 | 0.77 | 0.80 | 78 | empty |
| 3 | 577 | 0.68 | 0.78 | 46 | empty |
Compared structures
- 5JMC · Receptor binding domain of botulinum neurotoxin a in complex with rat SV2C · an experimental structure of the same protein · chain A against D, TM-score 0.13
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z2I6
- Elsewhere: UniProt Q9Z2I6 · AlphaFold DB Q9Z2I6
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