MolNFT v1 · #441486 · protein
AlphaFold monomer V2.0 prediction for extracellular sulfatase sulf-2 (Q8IWU5)
Q8IWU5: “AlphaFold monomer V2.0 prediction for extracellular sulfatase sulf-2 (Q8IWU5)”. 9 pockets (best druggability 0.65). MolNFT v1 #441486 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IWU5
- Type
- protein
- Length
- 870 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xFd3427947844fBBCAF505AA1B55322D4b1124c34
- Molecule
- Extracellular sulfatase sulf-2
- UniProt
- Q8IWU5
- Pockets
- 9 · best druggability 0.65
Structure
1 distinct chain · 27% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Extracellular sulfatase sulf-2 | protein | 870 | 27% helix, 14% strand | Q8IWU5 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 375 | 0.65 | 0.80 | 41 | empty |
| 2 | 320 | 0.59 | 0.77 | 39 | empty |
| 3 | 173 | 0.49 | 0.76 | 25 | empty |
| 4 | 163 | 0.44 | 0.75 | 21 | empty |
| 5 | 158 | 0.41 | 0.73 | 28 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IWU5
- Elsewhere: UniProt Q8IWU5 · AlphaFold DB Q8IWU5
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