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MolNFT v1 · #441342 · protein

AlphaFold monomer V2.0 prediction for suppressor of hairless protein (P28159)

P28159: “AlphaFold monomer V2.0 prediction for suppressor of hairless protein (P28159)”. 10 pockets (best druggability 0.61). MolNFT v1 #441342 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P28159
Type
protein
Length
594 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x35612D34a32C306CA4fc1edA9360D1F717e25950
Molecule
Suppressor of hairless protein
UniProt
P28159
Pockets
10 · best druggability 0.61

Structure

1 distinct chain · 14% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASuppressor of hairless proteinprotein59414% helix, 31% strandP28159

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14220.610.7640empty
21700.590.8227empty
33460.580.7639empty
42120.490.7524empty
51940.490.7628empty

Compared structures

  • 5E24 · Structure of the SU(H)-hairless-DNA repressor complex · an experimental structure of the same protein · chain A against F, TM-score 0.68

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