MolNFT v1 · #439899 · protein
AlphaFold monomer V2.0 prediction for speckle targeted PIP5K1A-regulated POLY(A) polymerase (D2HS90)
D2HS90: “AlphaFold monomer V2.0 prediction for speckle targeted PIP5K1A-regulated POLY(A) polymerase (D2HS90)”. 6 pockets (best druggability 0.79). MolNFT v1 #439899 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- D2HS90
- Type
- protein
- Length
- 869 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Speckle targeted PIP5K1A-regulated POLY(A) polymerase
- UniProt
- D2HS90
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 32% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Speckle targeted PIP5K1A-regulated POLY(A) polymerase | protein | 869 | 32% helix, 13% strand | D2HS90 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.79 | 0.82 | 66 | empty |
| 2 | 366 | 0.75 | 0.86 | 52 | empty |
| 3 | 235 | 0.53 | 0.77 | 33 | empty |
| 4 | 292 | 0.52 | 0.74 | 48 | empty |
| 5 | 108 | 0.36 | 0.73 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D2HS90
- Elsewhere: UniProt D2HS90 · AlphaFold DB D2HS90
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