MolNFT v1 · #439344 · protein

AlphaFold monomer V2.0 prediction for stanniocalcin-2 (O76061)

O76061: “AlphaFold monomer V2.0 prediction for stanniocalcin-2 (O76061)”. 2 pockets (best druggability 0.71). MolNFT v1 #439344 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O76061
Type: protein
Length: 302 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8841A75A4374915eB1e3A60827149042327e3c89
Molecule: Stanniocalcin-2
UniProt: O76061
Pockets: 2 · best druggability 0.71

Structure

1 distinct chain · 50% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stanniocalcin-2	protein	302	50% helix, 1% strand	O76061

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	436	0.71	0.81	38	empty
2	95	0.42	0.78	20	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

7Y5Q · Structure of 1:1 PAPP-A.STC2 complex(half map) · an experimental structure of the same protein · chain A against C, TM-score 0.55
8A7D · Partial dimer complex of PAPP-A and its inhibitor STC2 · an experimental structure of the same protein · chain A against P, TM-score 0.55
8A7E · PAPP-A dimer in complex with its inhibitor STC2 · an experimental structure of the same protein · chain A against A, TM-score 0.54
8HGH · Structure of 2:2 PAPP-A.STC2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.54

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O76061
Elsewhere: UniProt O76061 · AlphaFold DB O76061

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