MolNFT v1 · #439289 · protein
AlphaFold monomer V2.0 prediction for signal transducer and activator of transcription B (Q20977)
Q20977: “AlphaFold monomer V2.0 prediction for signal transducer and activator of transcription B (Q20977)”. 6 pockets (best druggability 0.77). MolNFT v1 #439289 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q20977
- Type
- protein
- Length
- 567 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
- Molecule
- Signal transducer and activator of transcription B
- UniProt
- Q20977
- Pockets
- 6 · best druggability 0.77
Structure
1 distinct chain · 44% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal transducer and activator of transcription B | protein | 567 | 44% helix, 20% strand | Q20977 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1039 | 0.77 | 0.79 | 68 | empty |
| 2 | 345 | 0.70 | 0.82 | 31 | empty |
| 3 | 96 | 0.48 | 0.81 | 22 | empty |
| 4 | 95 | 0.34 | 0.73 | 19 | empty |
| 5 | 81 | 0.33 | 0.74 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q20977
- Elsewhere: UniProt Q20977 · AlphaFold DB Q20977
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