MolNFT v1 · #439064 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 32A (Q8WU08)

Q8WU08: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 32A (Q8WU08)”. 2 pockets (best druggability 0.72). MolNFT v1 #439064 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8WU08
Type: protein
Length: 396 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xe9f3e03f1c0D674c8ca581614bB1f27977239e4c
Molecule: SERINE/THREONINE-protein kinase 32A
UniProt: Q8WU08
Pockets: 2 · best druggability 0.72

Structure

1 distinct chain · 39% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase 32A	protein	396	39% helix, 14% strand	Q8WU08

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	376	0.72	0.83	45	empty
2	62	0.35	0.78	18	empty

Compared structures

4FR4 · Crystal structure of human SERINE/THREONINE-protein kinase 32A (YANK1) · an experimental structure of the same protein · chain A against B, TM-score 0.84
4FR4 · Crystal structure of human serine/threonine-protein kinase 32A (YANK1) · an experimental structure of the same protein · chain A against B, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WU08
Elsewhere: UniProt Q8WU08 · AlphaFold DB Q8WU08

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