MolNFT v1 · #436388 · protein
AlphaFold monomer V2.0 prediction for tyrosine-protein kinase SRC64B (P00528)
P00528: “AlphaFold monomer V2.0 prediction for tyrosine-protein kinase SRC64B (P00528)”. 7 pockets (best druggability 0.73). MolNFT v1 #436388 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P00528
- Type
- protein
- Length
- 552 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4C9Ec21E2c4D42D2801b0CfEE695Ec148a47FF90
- Molecule
- Tyrosine-protein kinase SRC64B
- UniProt
- P00528
- Pockets
- 7 · best druggability 0.73
Structure
1 distinct chain · 25% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase SRC64B | protein | 552 | 25% helix, 20% strand | P00528 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 883 | 0.73 | 0.77 | 72 | empty |
| 2 | 646 | 0.70 | 0.78 | 62 | empty |
| 3 | 193 | 0.56 | 0.80 | 19 | empty |
| 4 | 58 | 0.42 | 0.82 | 16 | empty |
| 5 | 65 | 0.39 | 0.79 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00528
- Elsewhere: UniProt P00528 · AlphaFold DB P00528
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