MolNFT v1 · #436350 · protein
AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 12 (Q9P6L8)
Q9P6L8: “AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 12 (Q9P6L8)”. 10 pockets (best druggability 0.77). MolNFT v1 #436350 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9P6L8
- Type
- protein
- Length
- 1,134 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd6DfE5bdDd44c5887584131C31217ED4556a11e4
- Molecule
- Mediator of RNA polymerase II transcription subunit 12
- UniProt
- Q9P6L8
- Pockets
- 10 · best druggability 0.77
Structure
1 distinct chain · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 12 | protein | 1134 | 69% helix, 0% strand | Q9P6L8 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1081 | 0.77 | 0.78 | 96 | empty |
| 2 | 964 | 0.71 | 0.75 | 66 | empty |
| 3 | 485 | 0.63 | 0.76 | 43 | empty |
| 4 | 164 | 0.42 | 0.73 | 18 | empty |
| 5 | 77 | 0.42 | 0.79 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9P6L8
- Elsewhere: UniProt Q9P6L8 · AlphaFold DB Q9P6L8
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