MolNFT v1 · #436188 · protein
AlphaFold monomer V2.0 prediction for squalene synthase 1 (O48666)
O48666: “AlphaFold monomer V2.0 prediction for squalene synthase 1 (O48666)”. 5 pockets (best druggability 0.81). MolNFT v1 #436188 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O48666
- Type
- protein
- Length
- 415 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
- Molecule
- Squalene synthase 1
- UniProt
- O48666
- Pockets
- 5 · best druggability 0.81
Structure
1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Squalene synthase 1 | protein | 415 | 74% helix, 0% strand | O48666 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 896 | 0.81 | 0.83 | 79 | empty |
| 2 | 190 | 0.65 | 0.85 | 25 | empty |
| 3 | 151 | 0.42 | 0.74 | 33 | empty |
| 4 | 96 | 0.39 | 0.76 | 18 | empty |
| 5 | 52 | 0.30 | 0.75 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O48666
- Elsewhere: UniProt O48666 · AlphaFold DB O48666
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