MolNFT v1 · #436135 · protein
AlphaFold monomer V2.0 prediction for neurotrophin 1 (B7TB45)
B7TB45: “AlphaFold monomer V2.0 prediction for neurotrophin 1 (B7TB45)”. 7 pockets (best druggability 0.61). MolNFT v1 #436135 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7TB45
- Type
- protein
- Length
- 886 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x360F3648Ae1D86cC132fB5b953aD9558Bef99Aa0
- Molecule
- Neurotrophin 1
- UniProt
- B7TB45
- Pockets
- 7 · best druggability 0.61
Structure
1 distinct chain · 21% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neurotrophin 1 | protein | 886 | 21% helix, 8% strand | B7TB45 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 304 | 0.61 | 0.79 | 40 | empty |
| 2 | 238 | 0.48 | 0.73 | 27 | empty |
| 3 | 74 | 0.45 | 0.81 | 12 | empty |
| 4 | 144 | 0.44 | 0.76 | 19 | empty |
| 5 | 60 | 0.40 | 0.81 | 15 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7TB45
- Elsewhere: UniProt B7TB45 · AlphaFold DB B7TB45
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