MolNFT v1 · #435063 · protein
AlphaFold monomer V2.0 prediction for dual specificity protein kinase splb (P18161)
P18161: “AlphaFold monomer V2.0 prediction for dual specificity protein kinase splb (P18161)”. 5 pockets (best druggability 0.70). MolNFT v1 #435063 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P18161
- Type
- protein
- Length
- 1,155 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- Dual specificity protein kinase splb
- UniProt
- P18161
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 13% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity protein kinase splb | protein | 1155 | 13% helix, 6% strand | P18161 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 537 | 0.70 | 0.79 | 55 | empty |
| 2 | 265 | 0.50 | 0.74 | 29 | empty |
| 3 | 156 | 0.44 | 0.75 | 18 | empty |
| 4 | 62 | 0.39 | 0.80 | 14 | empty |
| 5 | 91 | 0.32 | 0.73 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18161
- Elsewhere: UniProt P18161 · AlphaFold DB P18161
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