MolNFT v1 · #434776 · protein
AlphaFold monomer V2.0 prediction for endoplasmic reticulum transmembrane helix translocase (P39986)
P39986: “AlphaFold monomer V2.0 prediction for endoplasmic reticulum transmembrane helix translocase (P39986)”. 19 pockets (best druggability 0.83). MolNFT v1 #434776 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P39986
- Type
- protein
- Length
- 1,215 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- Endoplasmic reticulum transmembrane helix translocase
- UniProt
- P39986
- Pockets
- 19 · best druggability 0.83
Structure
1 distinct chain · 45% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoplasmic reticulum transmembrane helix translocase | protein | 1215 | 45% helix, 18% strand | P39986 |
Pockets
19 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 418 | 0.83 | 0.91 | 43 | empty |
| 2 | 1009 | 0.82 | 0.83 | 95 | empty |
| 3 | 1037 | 0.79 | 0.81 | 96 | empty |
| 4 | 532 | 0.76 | 0.84 | 48 | empty |
| 5 | 411 | 0.61 | 0.76 | 41 | empty |
Compared structures
- 6XMQ · Structure of P5A-ATPase SPF1, AMP-pcp-bound form · an experimental structure of the same protein · chain A against A, TM-score 0.82
- 6XMS · Structure of P5A-ATPase SPF1, ALF4-bound form · an experimental structure of the same protein · chain A against A, TM-score 0.82
- 6XMP · Structure of P5A-ATPase SPF1, apo form · an experimental structure of the same protein · chain A against A, TM-score 0.82
- 6XMT · Structure of P5A-ATPase SPF1, BEF3-bound form · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 6XMU · Structure of P5A-ATPase Spf1, endogenous substrate-bound · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 6XMU · Structure of P5A-ATPase SPF1, endogenous substrate-bound · an experimental structure of the same protein · chain A against A, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39986
- Elsewhere: UniProt P39986 · AlphaFold DB P39986
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