MolNFT v1 · #434056 · protein

AlphaFold monomer V2.0 prediction for SAM pointed domain-containing ets transcription factor (O95238)

O95238: “AlphaFold monomer V2.0 prediction for SAM pointed domain-containing ets transcription factor (O95238)”. 2 pockets (best druggability 0.53). MolNFT v1 #434056 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O95238
Type: protein
Length: 335 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xc7B07e4CAc3aef57E90cd1aaf9cfB5A071144eAF
Molecule: SAM pointed domain-containing ets transcription factor
UniProt: O95238
Pockets: 2 · best druggability 0.53

Structure

1 distinct chain · 38% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SAM pointed domain-containing ets transcription factor	protein	335	38% helix, 4% strand	O95238

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	224	0.53	0.77	33	empty
2	138	0.41	0.74	16	empty

Compared structures

1YO5 · Analysis of the 2.0A crystal structure of the protein-DNA complex of human PDEF Ets… · an experimental structure of the same protein · chain A against C, TM-score 0.26
1YO5 · Analysis of the 2.0A crystal structure of the protein-DNA complex of human pdef ets… · an experimental structure of the same protein · chain A against C, TM-score 0.26
2DKX · Solution structure of the SAM_PNT-domain of ETS transcription factor PDEF (Prostate ets) · an experimental structure of the same protein · chain A against A, TM-score 0.26
2DKX · Solution structure of the SAM_PNT-domain of ets transcription factor pdef (prostate ets) · an experimental structure of the same protein · chain A against A, TM-score 0.26

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95238
Elsewhere: UniProt O95238 · AlphaFold DB O95238

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