MolNFT v1 · #434035 · protein
AlphaFold monomer V2.0 prediction for SH3 and px domain-containing protein 2A (Q5TCZ1)
Q5TCZ1: “AlphaFold monomer V2.0 prediction for SH3 and px domain-containing protein 2A (Q5TCZ1)”. 4 pockets (best druggability 0.52). MolNFT v1 #434035 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5TCZ1
- Type
- protein
- Length
- 1,133 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5062b2EC3CC3F0Bd724A9c14691EBC99DE6780B0
- Molecule
- SH3 and px domain-containing protein 2A
- UniProt
- Q5TCZ1
- Pockets
- 4 · best druggability 0.52
Structure
1 distinct chain · 8% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH3 and px domain-containing protein 2A | protein | 1133 | 8% helix, 15% strand | Q5TCZ1 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 252 | 0.52 | 0.75 | 19 | empty |
| 2 | 169 | 0.48 | 0.76 | 21 | empty |
| 3 | 112 | 0.42 | 0.77 | 19 | empty |
| 4 | 120 | 0.40 | 0.75 | 17 | empty |
Compared structures
- 2EGA · Solution structure of the first SH3 domain from human KIAA0418 protein · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2EGA · Solution structure of the first SH3 domain from human KIAA0418 protein · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2EKH · Solution structures of the SH3 domain of human KIAA0418 · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2EKH · Solution structures of the SH3 domain of human KIAA0418 · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2EGC · Solution structure of the fifth SH3 domain from human KIAA0418 protein · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2EGC · Solution structure of the fifth SH3 domain from human KIAA0418 protein · an experimental structure of the same protein · chain A against A, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5TCZ1
- Elsewhere: UniProt Q5TCZ1 · AlphaFold DB Q5TCZ1
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