MolNFT v1 · #432861 · protein
AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor sope (O52623)
O52623: “AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor sope (O52623)”. 3 pockets (best druggability 0.53). MolNFT v1 #432861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O52623
- Type
- protein
- Length
- 240 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xdF2b063d4B94F3f46D117B1af99A846bD4a59284
- Molecule
- Guanine nucleotide exchange factor sope
- UniProt
- O52623
- Pockets
- 3 · best druggability 0.53
Structure
1 distinct chain · 63% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor sope | protein | 240 | 63% helix, 3% strand | O52623 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 248 | 0.53 | 0.76 | 28 | empty |
| 2 | 118 | 0.48 | 0.79 | 22 | empty |
| 3 | 149 | 0.48 | 0.77 | 18 | empty |
Compared structures
- 1GZS · CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE GEF DOMAIN OF THE SALMONELLA TYPHIMURIUM… · an experimental structure of the same protein · chain A against B, TM-score 0.67
- 1GZS · Crystal structure of the complex between the gef domain of the salmonella typhimurium… · an experimental structure of the same protein · chain A against B, TM-score 0.67
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O52623
- Elsewhere: UniProt O52623 · AlphaFold DB O52623
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