MolNFT v1 · #432192 · protein
AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 7 (O14512)
O14512: “AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 7 (O14512)”. 6 pockets (best druggability 0.59). MolNFT v1 #432192 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O14512
- Type
- protein
- Length
- 581 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x71112d4fF7ebb3b617963c05f052289e073082FD
- Molecule
- Suppressor of cytokine signaling 7
- UniProt
- O14512
- Pockets
- 6 · best druggability 0.59
Structure
1 distinct chain · 15% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Suppressor of cytokine signaling 7 | protein | 581 | 15% helix, 6% strand | O14512 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 412 | 0.59 | 0.75 | 47 | empty |
| 2 | 160 | 0.43 | 0.74 | 20 | empty |
| 3 | 76 | 0.42 | 0.80 | 13 | empty |
| 4 | 80 | 0.37 | 0.76 | 19 | empty |
| 5 | 72 | 0.36 | 0.77 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14512
- Elsewhere: UniProt O14512 · AlphaFold DB O14512
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