MolNFT v1 · #432188 · protein
AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 5 (O54928)
O54928: “AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 5 (O54928)”. 3 pockets (best druggability 0.50). MolNFT v1 #432188 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O54928
- Type
- protein
- Length
- 536 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Suppressor of cytokine signaling 5
- UniProt
- O54928
- Pockets
- 3 · best druggability 0.50
Structure
1 distinct chain · 20% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Suppressor of cytokine signaling 5 | protein | 536 | 20% helix, 11% strand | O54928 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 186 | 0.50 | 0.77 | 27 | empty |
| 2 | 76 | 0.38 | 0.78 | 20 | empty |
| 3 | 60 | 0.29 | 0.74 | 17 | empty |
Compared structures
- 2N34 · NMR assignments and solution structure of the JAK interaction region of SOCS5 · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2N34 · NMR assignments and solution structure of the JAK interaction region of SOCS5 · an experimental structure of the same protein · chain A against A, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O54928
- Elsewhere: UniProt O54928 · AlphaFold DB O54928
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