MolNFT v1 · #432187 · protein
AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 5 (O75159)
O75159: “AlphaFold monomer V2.0 prediction for suppressor of cytokine signaling 5 (O75159)”. 4 pockets (best druggability 0.62). MolNFT v1 #432187 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O75159
- Type
- protein
- Length
- 536 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1D58c05FDe6847ACA12d0a86ffEe593119157D18
- Molecule
- Suppressor of cytokine signaling 5
- UniProt
- O75159
- Pockets
- 4 · best druggability 0.62
Structure
1 distinct chain · 20% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Suppressor of cytokine signaling 5 | protein | 536 | 20% helix, 10% strand | O75159 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 465 | 0.62 | 0.76 | 48 | empty |
| 2 | 64 | 0.36 | 0.78 | 17 | empty |
| 3 | 68 | 0.28 | 0.73 | 17 | empty |
| 4 | 60 | 0.27 | 0.72 | 11 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75159
- Elsewhere: UniProt O75159 · AlphaFold DB O75159
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