MolNFT v1 · #432143 · protein
AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 2 (O88908)
O88908: “AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 2 (O88908)”. 8 pockets (best druggability 0.87). MolNFT v1 #432143 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88908
- Type
- protein
- Length
- 525 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Sterol O-acyltransferase 2
- UniProt
- O88908
- Pockets
- 8 · best druggability 0.87
Structure
1 distinct chain · 68% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol O-acyltransferase 2 | protein | 525 | 68% helix, 1% strand | O88908 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1129 | 0.87 | 0.88 | 92 | empty |
| 2 | 263 | 0.67 | 0.82 | 21 | empty |
| 3 | 80 | 0.54 | 0.86 | 20 | empty |
| 4 | 223 | 0.50 | 0.75 | 25 | empty |
| 5 | 79 | 0.47 | 0.82 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88908
- Elsewhere: UniProt O88908 · AlphaFold DB O88908
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