MolNFT v1 · #432140 · protein
AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O70536)
O70536: “AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O70536)”. 10 pockets (best druggability 0.86). MolNFT v1 #432140 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O70536
- Type
- protein
- Length
- 545 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x04E06eD317348fEDb3659181320CA16FC3155761
- Molecule
- Sterol O-acyltransferase 1
- UniProt
- O70536
- Pockets
- 10 · best druggability 0.86
Structure
1 distinct chain · 70% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol O-acyltransferase 1 | protein | 545 | 70% helix, 1% strand | O70536 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 984 | 0.86 | 0.87 | 88 | empty |
| 2 | 299 | 0.67 | 0.81 | 29 | empty |
| 3 | 394 | 0.64 | 0.79 | 37 | empty |
| 4 | 91 | 0.63 | 0.89 | 18 | empty |
| 5 | 145 | 0.47 | 0.76 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O70536
- Elsewhere: UniProt O70536 · AlphaFold DB O70536
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