MolNFT v1 · #432139 · protein
AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (Q61263)
Q61263: “AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (Q61263)”. 6 pockets (best druggability 0.87). MolNFT v1 #432139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q61263
- Type
- protein
- Length
- 540 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- Sterol O-acyltransferase 1
- UniProt
- Q61263
- Pockets
- 6 · best druggability 0.87
Structure
1 distinct chain · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol O-acyltransferase 1 | protein | 540 | 73% helix, 1% strand | Q61263 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1097 | 0.87 | 0.87 | 86 | empty |
| 2 | 671 | 0.76 | 0.81 | 61 | empty |
| 3 | 117 | 0.53 | 0.82 | 26 | empty |
| 4 | 134 | 0.43 | 0.75 | 18 | empty |
| 5 | 116 | 0.40 | 0.75 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q61263
- Elsewhere: UniProt Q61263 · AlphaFold DB Q61263
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