MolNFT v1 · #432099 · protein
AlphaFold monomer V2.0 prediction for solute carrier organic anion transporter family member 1A2 (P46721)
P46721: “AlphaFold monomer V2.0 prediction for solute carrier organic anion transporter family member 1A2 (P46721)”. 8 pockets (best druggability 0.88). MolNFT v1 #432099 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P46721
- Type
- protein
- Length
- 670 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- Solute carrier organic anion transporter family member 1A2
- UniProt
- P46721
- Pockets
- 8 · best druggability 0.88
Structure
1 distinct chain · 62% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Solute carrier organic anion transporter family member 1A2 | protein | 670 | 62% helix, 6% strand | P46721 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1187 | 0.88 | 0.90 | 108 | empty |
| 2 | 337 | 0.58 | 0.76 | 33 | empty |
| 3 | 114 | 0.57 | 0.85 | 29 | empty |
| 4 | 231 | 0.55 | 0.78 | 26 | empty |
| 5 | 259 | 0.52 | 0.75 | 23 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46721
- Elsewhere: UniProt P46721 · AlphaFold DB P46721
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