MolNFT v1 · #432076 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-5 (B1H267)
B1H267: “AlphaFold monomer V2.0 prediction for sorting nexin-5 (B1H267)”. 4 pockets (best druggability 0.65). MolNFT v1 #432076 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B1H267
- Type
- protein
- Length
- 404 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- Sorting nexin-5
- UniProt
- B1H267
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 74% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-5 | protein | 404 | 74% helix, 7% strand | B1H267 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.65 | 0.76 | 58 | empty |
| 2 | 147 | 0.64 | 0.86 | 21 | empty |
| 3 | 622 | 0.63 | 0.74 | 60 | empty |
| 4 | 66 | 0.40 | 0.80 | 19 | empty |
Compared structures
- 3HPC · Crystal structure of SNX5-px domain in P21 space group · an experimental structure of the same protein · chain A against X, TM-score 0.35
- 3HPC · Crystal structure of SNX5-PX domain in P21 space group · an experimental structure of the same protein · chain A against X, TM-score 0.35
- 3HPB · Crystal structure of SNX5-px domain in P212121 space group · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 3HPB · Crystal structure of SNX5-PX domain in P212121 space group · an experimental structure of the same protein · chain A against A, TM-score 0.35
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1H267
- Elsewhere: UniProt B1H267 · AlphaFold DB B1H267
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