MolNFT v1 · #431977 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-1 (Q13596)
Q13596: “AlphaFold monomer V2.0 prediction for sorting nexin-1 (Q13596)”. 8 pockets (best druggability 0.64). MolNFT v1 #431977 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q13596
- Type
- protein
- Length
- 522 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x777B8f47014a4dE872e1b32733B9fD3c15840A7A
- Molecule
- Sorting nexin-1
- UniProt
- Q13596
- Pockets
- 8 · best druggability 0.64
Structure
1 distinct chain · 58% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-1 | protein | 522 | 58% helix, 5% strand | Q13596 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 430 | 0.64 | 0.77 | 44 | empty |
| 2 | 176 | 0.58 | 0.81 | 24 | empty |
| 3 | 197 | 0.55 | 0.79 | 22 | empty |
| 4 | 177 | 0.51 | 0.77 | 21 | empty |
| 5 | 103 | 0.49 | 0.81 | 22 | empty |
Compared structures
- 8A1G · Structure of the SNX1-SNX5 complex · an experimental structure of the same protein · chain A against A, TM-score 0.39
- 4FZS · Structure of human SNX1 BAR domain · an experimental structure of the same protein · chain A against A, TM-score 0.29
- 4FZS · Structure of human SNX1 bar domain · an experimental structure of the same protein · chain A against A, TM-score 0.29
- 2I4K · Solution Structure of the PX domain of Sorting Nexin 1 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2I4K · Solution structure of the px domain of sorting nexin 1 · an experimental structure of the same protein · chain A against A, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13596
- Elsewhere: UniProt Q13596 · AlphaFold DB Q13596
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