GL1X · GenesisL1 explorer

MolNFT v1 · #431957 · protein

AlphaFold monomer V2.0 prediction for sorting nexin-15 (Q9NRS6)

Q9NRS6: “AlphaFold monomer V2.0 prediction for sorting nexin-15 (Q9NRS6)”. 2 pockets (best druggability 0.59). MolNFT v1 #431957 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9NRS6
Type
protein
Length
342 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xe7fD32F422856e69Be28729279A8EB596328C29B
Molecule
Sorting nexin-15
UniProt
Q9NRS6
Pockets
2 · best druggability 0.59

Structure

1 distinct chain · 39% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASorting nexin-15protein34239% helix, 11% strandQ9NRS6

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12460.590.7929empty
23140.530.7432empty

Compared structures

  • 6MBI · Crystal Structure of SNX15 PX domain in domain swapped conformation form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.27
  • 6MBI · Crystal structure of SNX15 px domain in domain swapped conformation form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.27
  • 6ECM · Crystal structure of SNX15 px domain in domain swapped conformation · an experimental structure of the same protein · chain A against A, TM-score 0.26

Analyse

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