MolNFT v1 · #431953 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-14 (Q9Y5W7)
Q9Y5W7: “AlphaFold monomer V2.0 prediction for sorting nexin-14 (Q9Y5W7)”. 13 pockets (best druggability 0.79). MolNFT v1 #431953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y5W7
- Type
- protein
- Length
- 946 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9EB66588A5ad303fD557d27cBF610aaE56A05b53
- Molecule
- Sorting nexin-14
- UniProt
- Q9Y5W7
- Pockets
- 13 · best druggability 0.79
Structure
1 distinct chain · 55% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-14 | protein | 946 | 55% helix, 4% strand | Q9Y5W7 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 434 | 0.79 | 0.86 | 47 | empty |
| 2 | 363 | 0.76 | 0.86 | 49 | empty |
| 3 | 965 | 0.76 | 0.78 | 80 | empty |
| 4 | 1160 | 0.72 | 0.76 | 104 | empty |
| 5 | 473 | 0.66 | 0.78 | 35 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4BGJ · Crystal structure of the phox-homology domain of human sorting nexin 14 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BGJ · Crystal structure of the phox-homology domain of human sorting nexin 14 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4PQO · Structure of the human SNX14 px domain in space group I41 · an experimental structure of the same protein · chain A against A, TM-score 0.11
- 4PQO · Structure of the human SNX14 PX domain in space group I41 · an experimental structure of the same protein · chain A against A, TM-score 0.11
- 4PQP · Crystal structure of human SNX14 px domain in space group P43212 · an experimental structure of the same protein · chain A against B, TM-score 0.11
- 4PQP · Crystal structure of human SNX14 PX domain in space group P43212 · an experimental structure of the same protein · chain A against B, TM-score 0.11
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5W7
- Elsewhere: UniProt Q9Y5W7 · AlphaFold DB Q9Y5W7
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