MolNFT v1 · #431878 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SNT2 (P53127)
P53127: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SNT2 (P53127)”. 20 pockets (best druggability 0.72). MolNFT v1 #431878 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P53127
- Type
- protein
- Length
- 1,403 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb6B6a8B1b9C758652293B6ae405d26F422203cef
- Molecule
- E3 ubiquitin-protein ligase SNT2
- UniProt
- P53127
- Pockets
- 20 · best druggability 0.72
Structure
1 distinct chain · 31% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase SNT2 | protein | 1403 | 31% helix, 13% strand | P53127 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 757 | 0.72 | 0.78 | 63 | empty |
| 2 | 351 | 0.69 | 0.82 | 29 | empty |
| 3 | 209 | 0.63 | 0.82 | 30 | empty |
| 4 | 354 | 0.60 | 0.77 | 30 | empty |
| 5 | 281 | 0.60 | 0.79 | 28 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53127
- Elsewhere: UniProt P53127 · AlphaFold DB P53127
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