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MolNFT v1 · #431535 · protein

AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor CWF10 (O94316)

O94316: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor CWF10 (O94316)”. 9 pockets (best druggability 0.78). MolNFT v1 #431535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O94316
Type
protein
Length
984 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule
Pre-mRNA-splicing factor CWF10
UniProt
O94316
Pockets
9 · best druggability 0.78

Structure

1 distinct chain · 35% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-splicing factor CWF10protein98435% helix, 21% strandO94316

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11080.780.9825empty
211030.750.7885empty
33900.610.7644empty
42720.600.7927empty
51010.530.8325empty

Compared structures

  • 3JB9 · Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 3JB9 · Cryo-EM structure of the yeast spliceosome at 3.6 ångström resolution · an experimental structure of the same protein · chain A against B, TM-score 0.90

Analyse

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