MolNFT v1 · #431493 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF2 (A9JRZ0)
A9JRZ0: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF2 (A9JRZ0)”. 9 pockets (best druggability 0.70). MolNFT v1 #431493 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A9JRZ0
- Type
- protein
- Length
- 765 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x944f0A419Cb6d1485085105cB3499d49E5BF991A
- Molecule
- E3 ubiquitin-protein ligase SMURF2
- UniProt
- A9JRZ0
- Pockets
- 9 · best druggability 0.70
Structure
1 distinct chain · 31% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase SMURF2 | protein | 765 | 31% helix, 20% strand | A9JRZ0 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1089 | 0.70 | 0.75 | 78 | empty |
| 2 | 305 | 0.60 | 0.78 | 42 | empty |
| 3 | 257 | 0.57 | 0.79 | 25 | empty |
| 4 | 119 | 0.41 | 0.75 | 21 | empty |
| 5 | 140 | 0.40 | 0.74 | 25 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A9JRZ0
- Elsewhere: UniProt A9JRZ0 · AlphaFold DB A9JRZ0
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