MolNFT v1 · #431492 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF1 (Q9PUN2)

Q9PUN2: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF1 (Q9PUN2)”. 5 pockets (best druggability 0.77). MolNFT v1 #431492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9PUN2
Type: protein
Length: 731 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x01e3c8dae821844D1746b8af2984AbeaEaFbE719
Molecule: E3 ubiquitin-protein ligase SMURF1
UniProt: Q9PUN2
Pockets: 5 · best druggability 0.77

Structure

1 distinct chain · 30% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase SMURF1	protein	731	30% helix, 19% strand	Q9PUN2

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1197	0.77	0.79	115	empty
2	457	0.71	0.81	44	empty
3	154	0.55	0.81	23	empty
4	134	0.43	0.76	19	empty
5	85	0.34	0.74	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9PUN2
Elsewhere: UniProt Q9PUN2 · AlphaFold DB Q9PUN2

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