MolNFT v1 · #430012 · protein
AlphaFold monomer V2.0 prediction for slit and ntrk-like protein 2 (Q810C0)
Q810C0: “AlphaFold monomer V2.0 prediction for slit and ntrk-like protein 2 (Q810C0)”. 4 pockets (best druggability 0.81). MolNFT v1 #430012 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q810C0
- Type
- protein
- Length
- 846 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- Slit and ntrk-like protein 2
- UniProt
- Q810C0
- Pockets
- 4 · best druggability 0.81
Structure
1 distinct chain · 14% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Slit and ntrk-like protein 2 | protein | 846 | 14% helix, 12% strand | Q810C0 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 929 | 0.81 | 0.83 | 105 | empty |
| 2 | 157 | 0.47 | 0.77 | 21 | empty |
| 3 | 81 | 0.42 | 0.79 | 20 | empty |
| 4 | 103 | 0.37 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 4Y61 · Crystal structure of the complex between SLITRK2 LRR1 and ptp delta IG1-FN1 · an experimental structure of the same protein · chain A against B, TM-score 0.27
- 4Y61 · Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1 · an experimental structure of the same protein · chain A against B, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q810C0
- Elsewhere: UniProt Q810C0 · AlphaFold DB Q810C0
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