MolNFT v1 · #429909 · protein

AlphaFold monomer V2.0 prediction for DNA replication regulator SLD3 (Q09761)

Q09761: “AlphaFold monomer V2.0 prediction for DNA replication regulator SLD3 (Q09761)”. 5 pockets (best druggability 0.75). MolNFT v1 #429909 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q09761
Type: protein
Length: 699 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x58f53eCb168388AB0f1d3Cb9e5809dDe7f81eC02
Molecule: DNA replication regulator SLD3
UniProt: Q09761
Pockets: 5 · best druggability 0.75

Structure

1 distinct chain · 30% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA replication regulator SLD3	protein	699	30% helix, 4% strand	Q09761

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1116	0.75	0.78	109	empty
2	217	0.50	0.75	25	empty
3	72	0.35	0.76	16	empty
4	77	0.34	0.75	15	empty
5	78	0.32	0.74	12	empty

Compared structures

6HM3 · Crystal structure of Rad4 BRCT1,2 in complex with a Sld3 phosphopeptide · an experimental structure of the same protein · chain A against B, TM-score 0.03
6HM3 · Crystal structure of RAD4 BRCT1,2 in complex with a SLD3 phosphopeptide · an experimental structure of the same protein · chain A against B, TM-score 0.03

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q09761
Elsewhere: UniProt Q09761 · AlphaFold DB Q09761

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