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MolNFT v1 · #429713 · protein

AlphaFold monomer V2.0 prediction for actin cytoskeleton-regulatory complex protein SLA1 (P32790)

P32790: “AlphaFold monomer V2.0 prediction for actin cytoskeleton-regulatory complex protein SLA1 (P32790)”. 2 pockets (best druggability 0.41). MolNFT v1 #429713 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P32790
Type
protein
Length
1,244 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
Molecule
Actin cytoskeleton-regulatory complex protein SLA1
UniProt
P32790
Pockets
2 · best druggability 0.41

Structure

1 distinct chain · 12% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AActin cytoskeleton-regulatory complex protein SLA1protein124412% helix, 13% strandP32790

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11430.410.7419empty
2940.380.7621empty

Compared structures

  • 3IDW · Crystal structure of SLA1 homology domain 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 3IDW · Crystal structure of Sla1 homology domain 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2JT4 · Solution Structure of the Sla1 SH3-3-Ubiquitin Complex · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2JT4 · Solution structure of the SLA1 SH3-3-ubiquitin complex · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2HBP · Solution structure of SLA1 homology domain 1 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2HBP · Solution Structure of Sla1 Homology Domain 1 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2V1Q · Atomic-resolution structure of the yeast Sla1 SH3 domain 3 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2V1Q · Atomic-resolution structure of the yeast SLA1 SH3 domain 3 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 1Z9Z · Crystal structure of yeast sla1 SH3 domain 3 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 1Z9Z · Crystal structure of yeast SLA1 SH3 domain 3 · an experimental structure of the same protein · chain A against A, TM-score 0.05

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