MolNFT v1 · #429266 · protein
AlphaFold monomer V2.0 prediction for protein SIS2 (Q12600)
Q12600: “AlphaFold monomer V2.0 prediction for protein SIS2 (Q12600)”. 4 pockets (best druggability 0.57). MolNFT v1 #429266 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q12600
- Type
- protein
- Length
- 531 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- Protein SIS2
- UniProt
- Q12600
- Pockets
- 4 · best druggability 0.57
Structure
1 distinct chain · 18% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein SIS2 | protein | 531 | 18% helix, 8% strand | Q12600 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.57 | 0.78 | 47 | empty |
| 2 | 207 | 0.50 | 0.76 | 31 | empty |
| 3 | 107 | 0.37 | 0.75 | 21 | empty |
| 4 | 88 | 0.33 | 0.73 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12600
- Elsewhere: UniProt Q12600 · AlphaFold DB Q12600
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